请帮忙看下报告

各位姐妹：

      今天刚拿到的中期唐氏报告，医生说高危（数据如下），不明白哪项出了问题，医生说要做羊水穿刺，有点怕怕的。报告是18周多做的，现23周多。早期唐氏低危，现怀二胎，头胎小孩健康。请帮帮我看看哪项有问题，谢谢！

孕中期唐氏筛查

项目                                                                    结果                                            参考值                         单位
甲胎蛋白AFP（AFPCS）                                       58。3                                                                             U/ml

甲胎蛋白中位数倍数MOM（MOMA）                     1.08                                            0.6-2.6                         MOM

游离 HCG（ul  hcg)                                               5.0                                                                                  ng/ml

 -HCG中位数倍数（MOMF）                                   0。41                                         0。4-2。4                    MOM

非结合雌三醇（UE3）（UE3）                             4。7                                                                                  nmol/L

UE3中位数倍数（MOME）                                    0。67                                          >0.73                            MOM

年龄风险度age(age)                                             1/1270

AFP+年龄风险度 AFP+AGE（AFP+AGE）            1/1900

21- 三体风险度（21-Tri)                                       1/50000                                     <1/270

18- 三体风险度 (18-Tri)                                        1/12100                                    <1/350

神经管缺陷风险度（NTD）                                   NEGATIVE                                   <1/1000