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[精子畸形]

【处男贴】从拿数据看畸形精子对人类胚胎的影响

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71060 楼主
谢谢亲的鼓励,爱你!
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想必来这个版块的基本上都是关注Sperm(精子)质量的,哥不慎也进入到teratozoospermia (畸形精子症)的一员,想必我的情况大家没兴趣知道吧,我直接上论文。

【这个帖子的内容主要是关于teratozoospermia(畸形精子症) 与胚胎质量的关系,反感崇洋媚外者请绕行。】
论文一:

Purpose: To reevaluate the effect of isolated teratozoospermia on IVF and determine if there was any therapeutic benefit to isolated teratozoospermia by ICSI, since there are no widely accepted criteria for the treatment technique about isolated teratozoospermia. Methods: A total of 441 couples with >20 million and progressive motility >30 % sperm undergoing their first IVF/ICSI cycle were included in the study between 2008 and 2010, for whom at least 8 oocytes were retrived. Isolated teratozoospermia was diagnosed in 183 of the included couples, and the rest couples (normal sperm morphology) were studied as control. Sibling oocytes were randomized to be inseminated either by ICSI or IVF. Fertilization rate, embryo quality, pregnancy rate, implantation rate and spontaneous abortion rate were assessed. Results: There was no difference in the percentage of eggs fertilized, implantation rate, pregnancy rate and spontaneous abortion rate between conventional IVF and ICSI regardless of the percentage of normal morphology. The day 3 embryonic morphology and rate of development were not different despite the insemination method and percentage of normal morphology. Conclusion Because isolated teratozoospermia did not influence the major indices of IVF and the unnecessary use of ICSI is time-consuming, costly and potential risks, couples with isolatedteratozoospermia need not be subjected to ICSI.
名词解释:ICSI就是传说中的二代试管。IVF是体外授精。我个人觉得IVF的范围更大一些,三代二代试管应该都属于IVF。
这篇论文的主要意图是评估有畸形精子症的夫妇进行ICSI时,与正常夫妇(精子邢台正常,无畸形或畸形率很低)的体外受精胚胎进行了对比,通过抽样的数据说明胚胎的受精率、移植率( implantation rate这个我不是医生不清楚指的是不是移植成功率)、怀孕率和意外流产率在用ICSI和正常怀孕夫妇间没有不同。

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